RECOMBINANT TRYPSIN, USP

cGMP Grade

Trypsin is a serine protease with a plethora of industrial applications including Bio ‒ pharmaceutical manufacturing as it precisely cleaves peptide chains mainly at the C-terminus of Lysine and Arginine, except when either is followed by Proline. Derived from Porcine pancreas in the native form for use in Biopharma production, Trypsin has been under onstant Regulatory surveillance for safeguarding the product consistency and safety of the biopharmaceutical.

To meet the demands of the high quality Biopharmaceutical and the stringent Regulatory requisite, DK Biopharma has revamped the Trypsin gene as per USP sequence into Escherichia coli for recombinant gene expression. The result is a recombinant enzyme with nonpareil purity and properties of its native counterpart. The Recombinant Trypsin is animal component-free and is produced under regulations of current good manufacturing practice (cGMP).

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RECOMBINANT CARBOXYPEPTIDASE B (CPB)

cGMP Grade

Carboxypeptidase B (CPB) is a serine protease with specific applications in the Biopharmaceutical manufacturing as it precisely cleaves basic amino acids, Arginine and Lysine from the C-terminus of proteins or peptide chains. The native form is derived from a varied animal sources, including the porcine, bovine and rattus origin for use in Biopharma production. Due to its extensive use in the Biopharmaceutical manufacturing CPB has been under constant Regulatory surveillance for ensuring safer and cleaner biopharma products.

To meet the demands of the high quality Biopharmaceutical and the stringent Regulatory requisite, DK Biopharma has transformed the rat Carboxypeptidase B gene into Escherichia coli for recombinant protein expression. The result is a recombinant enzyme with nonpareil purity and properties of its native counterpart. The Recombinant CPB is Animal Origin Free (AOF) and is produced under regulations of current good manufacturing practice (cGMP).

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